But what happens when the requirements change?
This is a reminder for all parents.
The state of Indiana has new requirements for incoming kindergartners and seniors in high school.
Students will fill empty classrooms starting next week, but new vaccine requirements have some parents worried their child may not be allowed in.
Dana Winchester's son is starting kindergarten. She wasn't aware of the new vaccines until a few weeks ago.
"Well, school's starting on Tuesday and there's no way I was going to be able to get it done in that amount of time, so I didn't even know if he was going to be able to start school," said Winchester.
Kindergarten students will now need two doses of Hepatitis A vaccine in addition to the previously required shots. But the Hep-A doses are given 6 months apart, and many doctors are unavailable for appointments until after school begins.
"When I did call his doctor the next available appointment was like September 3rd. Well, that's way after school starts so that wasn't going to help me out at all," said Winchester.
Because of the minimum intervals between vaccine doses, planning ahead will prevent future headaches.
"I was really worried, I was getting very stressed out about it," said Winchester.
Winchester learned as long as her son has his first dose, he's okay to start class.
Officials say, there are many different places to go to get your child's records updated.
Joni Wise, with the Vigo County Health Department said, "Get a hold of your health care provider, CVS, Walgreens, MedExpress, and get your children's immunization up to date so they'll be ready for school."
Many kids try to avoid getting a shot, but a quick pinch could save them from getting sick.
"Vaccine preventable illness is out there. We've seen mumps outbreak in Vigo County, chickenpox outbreak, it's extremely important to have your children immunized because shots are the best front-line protection regarding vaccine preventable disease," said Wise.
And not to forget, the stickers and lollipops awarded for that second of bravery.
Students entering grade 12 may need an additional vaccine against meningitis, it all depends on when they received their first dose.
One more reminder, if your child is going off to college in a few weeks, most universities require new vaccines before coming to campus
Illinois schools are similar to Indiana in that there is now a hepatitis shot requirement.
Click here for a link to Illinois requirements.
Click here for a link to Indiana requirements.